ABOUT

Welcome to WOCJC-12

東京工業大学，国立清華大学（National Tsing Hua University, NTHU）

韓国高等科学技術院（Korea Advanced Institute of Science and Technology, KAIST）で、

有機化学及び関連化学を学ぶ大学院生と研究者のための研究交流ワークショップ

12th Workshop on Organic Chemistry for Junior Chemists (WOCJC-12) を、

令和6年（2024）年1月14日（日）〜17日（水）に東京工業大学すずかけ台キャンパスで開催いたします。

STAFF

Chairman

Ikuyoshi Tomita (Tokyo Tech)

Co-chairman

Kui-Thong Tan (NTHU)

Sungwoo Hong (KAIST)

Local committee

(Tokyo Tech)

Hiroyuki Nakamura / Toshihiro Okamoto

Kei Goto / Shinsuke Inagi

Ken Omori / Hiroshi Tanaka

Katsunori / Tanaka Takeshi Hata

Michito Yoshizawa / Yoshiaki Shoji

SPEAKERS

Plenary Speakers

Sungwoo Hong (KAIST) “Investigation of Catalytic System for the Efficient Synthesis of Privileged Scaffolds”

Ching-Ching Yu (NTHU) “Substrate-controlled Enzymatic Glycosylation for Complex Oligosaccharide Synthesis”

Katsunori Tanaka (Tokyo Tech) “Therapeutic In Vivo Synthetic Chemistry”

Invited Speakers

Hyunwoo Kim (KAIST) “Ligand-Controlled Regioselective and Enantioselective Functionalization of Dienes”

Kui-Thong Tan (NTHU) “Affinity-Switchable Biotin Binding: A New Signal Transduction Approach for Rapid Molecule Analyses”

Ken Ohmori (Tokyo Tech) “Unlocking the Complexity: Feasible Synthetic Access to Natural Products based on

Symmetrization/Desymmetrization Strategy”

PROGRAM

January 14, Sunday

18:00- Welcome Party

January 15, Monday

8:30–9:00 Registration

9:00–9:10 Opening Ceremony

9:10–9:40 Plenary Lecture 1

PL-01

Sungwoo Hong (KAIST)

“Investigation of Catalytic System for the Efficient Synthesis of Privileged Scaffolds”

9:40–10:00 Invited Lecture 1

IL-01

Ken Ohmori (Tokyo Tech)

“Unlocking the Complexity: Feasible Synthetic Access to Natural Products based on Symmetrization/Desymmetrization Strategy”

10:00–10:20 Break

10:20–11:50 Oral Presentations

OP-01

Yun-Qiao Liu, Kui-Thong Tan (NTHU)

“Bioconjugationof Gold Nanoparticles via Alkyne-Gold Interaction”

OP-02

Shotaro Otaka, Tsukasa Sano, Satoru

Kuwano, Kei Goto (Tokyo Tech)

“Model Study on Oxidative Modification of Cysteine Utilizing a Molecular Cradle”

OP-03

Duc Tai Nguyen, Insung S. Choi (KAIST)

“Chemical Control over Self-Assembly of Flavonoids and Fe3+ Ions in Biphasic Water-Oil Systems”

OP-04

Tomohiro Imai, Ryoyu Hifumi, Shinsuke Inagi, Ikuyoshi Tomita (Tokyo Tech)

“Design and Synthesis of Highly Alkaline-tolerant Triarylsulfonium Salts and Their Applications to Anion Exchange Membrane Materials”

OP-05

Meng-Che Li, Sheng-Kai Wang (NTHU)

“Structure conversion of modifying polyproline”

OP-06

Ryoya Kamiki, Tomohiro Kubo, Kotaro Satoh (Tokyo Tech)

“Design of Degradable Vinyl Polymers by Radical Ring-Opening Copolymerization of Cyclic Thiocarbonyl Monomers”

11:50–13:15 Lunch

13:15–14:25 Short Talks

ST-01

Sangeun Yeom, Ken Ohmori (Tokyo Tech)

“Facile construction of benzotropone scaffold: one-pot annulation strategy using dioxinone derivative”

ST-02

Bo-An Liao, Yi-Chou Tsai (NTHU)

“Paddlewheel Dicobalt Complexes with Various Oxidation States in the Metal Centers”

ST-03

Shintaro Hamada, Ken Tanaka (Tokyo Tech)

“Enantioselective construction of tetrasubstituted fluorinated stereocenters by Rh-catalyzed [2+2+2] cycloaddition”

ST-04

Hahyoun Park, Cham Bi Seo, Jaesook Yun, Hyunwoo Kim (KAIST)

“Chiral Recognition of Bicyclic Bridgehead Boronates with Cobalt Complexes by 19F NMR Spectroscopy”

ST-05

Shion Masano, Kei Goto, Kosuke Ono (Tokyo Tech)

“Covalent Template Synthesis of a CHO-Functionalized Oligophenylene Ring”

ST-06

Kai-Eng Ooi, Yung-Jen Cheng, Cheng-Huan Liu, Ching-Ching Yu (NTHU)

“Investigating the substrate tolerance and catalytic mechanism of α1,3/4 - fucosyltransferase from Bacteroides fragilis”

ST-07

Suguru Iwai, Ikuyoshi Tomita, Shinsuke Inagi (Tokyo Tech)

“Electropolymerization of Aromatic Monomers Using a Pressure-driven Bipolar Electrochemical System”

ST-08

Seungmo Seo, Sunkyu Han (KAIST)

“Total Synthesis of (-)-Flueggenine A”

ST-09

Yu-En Huang, Kakeru Konagaya, Shigekazu Ito (Tokyo Tech)

“Difluoromethylborates as the HF2C· Sources for the Isonitrile Insertion Affording Difluoromethylated Phenanthridines”

ST-10

Sen-Hung Hsieh, Fu-Te Tsai, Wen-Feng Liaw (NTHU)

“3A Element-Modified Copper-Doped Graphitic Carbon Nitride for Heterogeneous Photocatalytic CO2 Reduction”

ST-11

Riko Kashima, Tomohiro Kubo, Kotaro Satoh (Tokyo Tech)

“Hydrophilic Bio-Based Polymers from Glycerol-Derived Cyclic Vinyl Ethers”

ST-12

Hayoung Shin, Yoonsu Park (KAIST)

“Mechanochemical Dinitrogen Activation for Organic Synthesis”

ST-13

Takuya Hisamitsu, Ken Ohmori (Tokyo Tech) “Synthetic study on neoabyssomicin D”

ST-14

Yu-Ching Feng, Kui-Thong Tan (NTHU)

“Affinity-Tunable Semisynthetic Protein Switches for Small Molecule Detection via Microarray Platform”

ST-15

Nao Yamamoto, Kohei Umedera, Taiki Morita, Hiroyuki Nakamura (Tokyo Tech)

“Asymmetric construction of bridged oxopiperazines for peptidomimetics design”

ST-16

Hyung-Joon Kang, Sungwoo Hong (KAIST)

“Nickel-Catalyzed Kinetic Resolution of Racemic Unactivated Alkenes Enabled by Ligand Participation”

ST-17

Kakeru Miyamoto, Taiki Morita, Hiroyuki Nakamura (Tokyo Tech) “Synthetic studies on Dentigerumycin A”

ST-18

Yu-Wei Chuang, Yu-Heng Wang (NTHU)

“Electrocatalysis C(sp3)-H Bond Oxygenation through High–Valent Metal– Oxo Species: Water as an Oxygen source”

ST-19

Yukihiro Murata, Takanori Fukushima, Yoshiaki Shoji (Tokyo Tech)

“Synthesis of a Macrocyclic Boron Cation and Its Derivatization into Polycyclic Boranes”

ST-20

Minsoo Kim, Yoonsu Park (KAIST)

“Electrocatalytic Ammonia Oxidation in Water Using a Copper-based Molecular Electrocatalyst”

ST-21

Takejiro Ogawa, Fumitaka Ishiwari, Ryosuke Takehara, Yoshiaki Shoji, Takanori Fukushima (Tokyo Tech)

“Synthesis of a Two-Dimensional Assembly of Molecular Rotor Units Using a Tripodal Triptycene-Based Supramolecular Scaffold”

ST-22

Koki Nishi, Koki Yamaguchi, Takeshi Hata (Tokyo Tech)

“Facile Preparation of Functionalized Nitrones from Nitro compounds and Organozinc Reagents”

14:25–14:45 Break

14:45–16:15 Poster Presentations

16:15–16:35 Break

16:35–17:20 Oral Presentations

OP-07

Hyeyun Keum, Harin Ryoo, Dongwook Kim, Sukbok Chang (KAIST)

“Amidative β‑Scission of Alcohols Enabled by Dual Catalysis of Photoredox Proton-Coupled Electron Transfer and

Inner-Sphere Ni-Nitrenoid Transfer”

OP-08

Vaibhav Pramod Charpe†, Mahima Gupta†, and Kuo Chu Hwang (NTHU)

“Visible-Light-Induced Oxidative α-keto-Dichlorination of Arylalkynes by CuCl2 at Room Temperature”

OP-09

Jieun Kim, Sungwoo Hong (KAIST)

“Sulfonyl Radical Formation via β-fragmentation of Aminophosphoranyl Radicals”

January 16, Tuesday

9:00–9:30 Plenary Lecture 2

PL-02

Ching-Ching Yu (NTHU)

“Substrate-controlled Enzymatic Glycosylation for Complex Oligosaccharide Synthesis”

9:30–9:50 Invited Lecture 2

IL-02

Hyunwoo Kim (KAIST)

“Ligand-Controlled Regioselective and Enantioselective Functionalization of Dienes”

9:50–10:10 Break

10:10–11:55 Oral Presentations

OP-10

Yung-Yu Su, Yan-Ting Kuo, Hong-Jyune Lin, Chun-Cheng Lin (NTHU) “Synthesis of Ganglioside SJG-2 Glycan”

OP-11

Naoki Narita, Ken Ohmori (Tokyo Tech)

“Synthetic Study on Flavan Oligomers: Applicability of Flow Conditions”

OP-12

Yoo-jin Lee, Sunkyu Han (KAIST)

“Total Synthesis of Dimeric Epoxyquinoids”

OP-13

Masato Tsuda, Taiki Morita, Yuto Morita, Jun Takaya, Hiroyuki Nakamura (Tokyo Tech)

“Skeletal Editing by Ring Expansion of Heterocycles via Methylene Insertion into Nitrogen-Heteroatom bonds using a Zinc Carbenoid”

OP-14

Yueh-Hua Liu, Chin-Wei Chuang, Guan-Ru Huang, Shiang-Fu Hung, Chan- Wei Hsu, Chiu-Han Hwang, Chien-Tien Chen (NTHU)

“Enantioselective Radical-Type 1,2-Difunctionalization to Styrenes Catalyzed by Chiral Vanadyl Complexes”

OP-15

Jumi Kim, Hyunwoo Kim (KAIST)

“Chiral Discrimination of Monosaccharides Derivatized with 2-Fluorophenyl Hydrazine Using 19F NMR Spectroscopy”

OP-16

Futo Morita, Yu Sato, Gaku Fukuhara, Masanobu Uchiyama, Hidehiro Uekusa, Ken Tanaka (Tokyo Tech)

“Design and synthesis of 3D π-extended carbohelicenes for high brightness circularly polarized luminescence”

11:55–13:50 Lunch

13:50–15:05 Oral Presentations

OP-17

Tatsuya Kobayashi, Kenshiro Yamada, Tsung-Che Chang, Ambara R. Pradipta, Katsunori Tanaka (Tokyo Tech)

“Development and Therapeutic Applications of In Vivo Patrolling Molecule”

OP-18

Mei-Ting Lin, Cheng-En You, Yu-Ting Huang, Ching-Ching Yu (NTHU)

“Gram-scale chemoenzymatic synthesis of human milk oligosaccharides using crude cell lysate”

OP-19

Yuria Takahashi, Kazuki Terashima, Ambara R. Pradipta, Katsunori Tanaka (Tokyo Tech)

“Cancer Therapy through [3+2] Cycloaddition Reaction with Patient-Derived Cancer Metabolites in Mouse Models”

OP-20

Jungwoo Hong, Hee-Seung Lee (KAIST)

“Cyclic β-Amino Acid Incorporated with Thioether Functionality and Versatile Post-synthetic Modifications of Helical β-Peptides”

OP-21

Yujie Shao, Kazuki Miura, Yasunobu Asawa, Taiki Morita, Hiroyuki Nakamura (Tokyo Tech)

“Discovery of Disubstituted Carboranes as Novel Heat Shock Protein 90 Inhibitors Disrupting HSP90-HSF1 Interaction”

15:05–15:25 Break

15:25–16:25 Oral Presentations

OP-22

Chih-Ying Lin, Fu-Te Tsai, Wen-Feng Liaw (NTHU)

“Hetero Dual-Atom Metal Catalyst for Acidic Carbon Dioxide Electroreduction Reaction”

OP-23

Kohei Taniguchi, Tomoyuki Kurioka, Kosuke Sato, Ikuyoshi Tomita, Shinsuke Inagi (Tokyo Tech)

“Main Chain Functionalization of Thiophene–Fluorene Alternating Copolymers via Anodic C–H Phosphonylation”

OP-24

Dabon Lee, Soon Hyeok Hong (KAIST)

“Development of Densely Hydroxylated Polymers via Ring Opening Metathesis Polymerization of Cyclohexene Derivatives”

OP-25

Sota Yamamoto, Tomohiro Kubo, Kotaro Satoh (Tokyo Tech)

“Interlocking Degradation of Vinyl Polymers Triggered by Pendant- Responsive Comonomers”

16:25–16:45 Break

16:45–17:05 Invited Lecture 3

IL-03